Vitamin D Level Linked to Breast Tumor Size

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In a retrospective study, Barbara Brouwers, PhD of the University of Leuven in Belgium found that women who have higher levels of vitamin D when diagnosed with breast cancer appear to have smaller tumors on average.

"Lower vitamin D levels were correlated with much bigger tumors," says Dr. Brouwers. "We also saw that higher vitamin D levels were associated with better outcomes, but it wasn't significant."

Studies have shown that vitamin D status is important in many chronic disease and illness of various types. Low vitamin D levels have been associated with higher breast and other cancer risks and in some studies higher levels have been shown to correlate with better outcomes for some cancers.

Brouwers and her colleagues look at data from 1,800 breast cancer patients treated at the University of Leuven from 2003 to 2010 which included data on serum 25-hydroxy vitamin D3 collected at diagnosis. Following those patients for four years showed that lower vitamin D levels were significantly associated with larger tumor sizes (every 0.4ng/mL decrease in level linked to 1cm in tumor increase).

Accompanying this, to no surprise, was a 27% lower risk of death per 10ng/mL increase in vitamin D levels at diagnosis. Close the same could be said for risk of relapse as well.


 
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